UCSF Adult Restricted Antimicrobials

sort ascending
Voriconazole

Restricted to ID or Antimicrobial Stewardship except:

1) Prophylaxis against fungal infections on the hematology/BMT/lung transplant services​

2) Suspected or documented fungal pneumonia in the hematology/BMT/lung transplant services​

3) Empiric therapy for prolonged febrile neutropenia in hematology/oncology/BMT patient
Tigecycline

Restricted to ID or Antimicrobial Stewardship 
Tedizolid

Restricted to ID or Antimicrobial Stewardship 
Posaconazole

IV formulation - Restriced to ID or Antimicrobial Stewardship 

PO formulation - Restricted to ID or Antimicrobial Stewardship except:

1) Prophylaxis against fungal infections in patients on the hematology/BMT or lung transplant services with an intolerance of or contraindications to voriconazole

2) Suspected or documented fungal pneumonia in the hematology/BMT or lung transplant services

3) Empiric therapy for prolonged febrile neutropenia in hematology/oncology/BMT patient
Polymyxin B

Restricted to ID or Antimicrobial Stewardship 
Plazomicin

Restricted to ID or Antimicrobial Stewardship 
Peramivir

Restricted to ID or Antimicrobial Stewardship 
Pentamidine IV

Restricted to ID or Antimicrobial Stewardship 
Oritavancin

Restricted to ID or Antimicrobial Stewardship 
Omadacycline

Oral formulation 

Restricted to ID or Antimicrobial Stewardship except:

1) Continuation of prior therapy
Miltefosine

Restricted to ID or Antimicrobial Stewardship with exceptions:

1) Continuation of therapy 
Micafungin

Restricted to ID or Antimicrobial Stewardship except:

1) Documented sterile site (not urine or respiratory) infection  with microbiologically confirmed Candida glabrata or Candida kruseii

2) Documented sterile site infection (not urine or respiratory) infection with yeast, pending species identification

3) Prophylaxis against fungal infections in patients on the hematology/oncology/BMT service with intolerance of or contraindications to azoles

4) Empiric therapy for prolonged febrile neutropenia in hematology/oncology/BMT patient
Meropenem/vaborbactam

Restricted to ID or Antimicrobial Stewardship except:

1) Continuation of prior therapy
Maribavir

Restricted to ID or Antimicrobial Stewardship except:

1) Continuation of prior therapy
Letermovir

Restricted to ID or Antimicrobial Stewardship except for:

1)  Adult malignant hematology service - for prophylaxis only per service guidelines
2)  Prophylaxis of CMV disease in high-risk kidney transplant recipients
3)  Continuation of current outpatient therapy
Isavuconazole

Restricted to ID or Antimicrobial Stewardship except:​

1) Documented or suspected fungal pneumonia in a patient with prolonged QTc interval​

2) Prophylaxis against fungal infections in patients on the hematology/BMT service or lung transplant service with prolonged QTc interval or concurrent QTc prolonging medications.
Imipenem/cilastatin/relebactam

Restricted to ID or Antimicrobial Stewardship 
Imipenem/cilastatin

Restricted to ID or Antimicrobial Stewardship 
Foscarnet

Restricted to ID or Antimicrobial Stewardship except 

1) For treatment or prophylaxis against viral infection in BMT patient

 
Fecal microbiota spores, live—brpk (Vowst)

Restricted to ID/ASP for use in select adults with recurrent CDI who are expected to be hospitalized > 14 days after C. difficile episode.

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