Primary tabs
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl >90 mL/min | 60-90 mL/min | 30-60 mL/min | 15-30 mL/min |
|---|---|---|---|---|
|
All Indications 1.25 g = imipenem 500 mg + cilastatin 500 mg + relebatam 250 mg |
1.25 g IV q6h | 1 g IV q6h | 750 mg IV q6h | 500 mg IV q6h |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
|
All Indications 1.25 g = imipenem 500 mg + cilastatin 500 mg + relebatam 250 mg |
500 mg IV q6h | No data |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
Restricted to ID or Antimicrobial Stewardship