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Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl >10 mL/min | <10 mL/min |
|---|---|---|
| All Indications |
480 mg IV/PO q24h With concomitant cyclosoprine: 240 mg IV/PO q24h |
No dosing recommendations available |
ZSFG: Non-formulary
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dosing | Notes |
|---|---|---|
| All Indications |
480 mg IV/PO q24h With concomitant cyclosoprine: 240 mg IV/PO q24h |
No dosing recommendations available for hemodialysis |
ZSFG: Non-formulary
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
Restricted to ID or Antimicrobial Stewardship except for:
1) Adult malignant hematology service - for prophylaxis only per service guidelines
2) Prophylaxis of CMV disease in high-risk kidney transplant recipients
3) Continuation of current outpatient therapy
ZSFG: Non-formulary