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Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl >60 mL/min | 30-60 mL/min | <30 mL/min |
|---|---|---|---|
| All Indications | 300/100 mg PO BID | 150/100 mg PO BID | Not recommended |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
| All Indications | No data | No data |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
Review medications for potential drug interactions.
Restricted to ASP or ID consult service (with exceptions):
- Inpatients (or those in the ED pending admission) with mild-moderate COVID-19 with symptom onset within 5 days and high-risk for progression who are admitted for reasons other than COVID-19 (see CDC Website for high-risk criteria)