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Dosing Weights
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl > = 10 ml/min | CrCl < 10 ml/min |
|---|---|---|
| Pneumocystis pneumonia | 4 mg/kg IV q24h | 4 mg/kg IV q36h |
*The current prescribing information does not provide specific renal adjustments and may need to consider other dosing outside of these recommendations.
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
| Pneumocystis pneumonia | 4 mg/kg IV q24h (no adjustment for hemodialysis) | 4 mg/kg IV q24h (no adjustment for hemodialysis) |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
*The current prescribing information does not provide specific renal adjustments and may need to consider other dosing outside of these recommendations.
Restricted to ID or Antimicrobial Stewardship