UCSF Adult Restricted Antimicrobials

AmBisome (liposomal amphotericin B)

Restricted to ID or Antimicrobial Stewardship except:

1) Documented or suspected fungal pneumonia in a patient intolerant of or with contraindications to azoles

2) Prophylaxis against fungal infections in patients on the hematology/BMT service or lung transplant service

3) Empiric therapy for prolonged febrile neutropenia in hematology/oncology/BMT patient 

Amikacin

Restricted to ID or Antimicrobial Stewardship for IV amikacin 

Artesunate

Restricted to ID or Antimicrobial Stewardship

Baloxavir marboxil

Restricted to ID or Antimicrobial Stewardship

Cefiderocol

Restricted to ID or Antimicrobial Stewardship

Ceftaroline

Restricted to ID or Antimicrobial Stewardship

Ceftazidime/avibactam (Avycaz)

Restricted to ID or Antimicrobial Stewardship

Ceftolozane/tazobactam (Zerbaxa)

Restricted to ID or Antimicrobial Stewardship

Cidofovir

Restrict to ID or Antimicrobial Stewardship except:

1) For treatment or prophylaxis against viral infection in a BMT patient

Colistin IV

Restricted to ID or Antimicrobial Stewardship

*Inhaled use of colistin is allowed for unrestricted use in prophylaxis in lung transplant.

Dalbavancin

Restricted to ID or Antimicrobial Stewardship

Daptomycin

Restricted to ID or Antimicrobial Stewardship

Eravacycline

Restricted to ID or Antimicrobial Stewardship 

Foscarnet

Restricted to ID or Antimicrobial Stewardship except 

1) For treatment or prophylaxis against viral infection in BMT patient

 

Imipenem/cilastatin

Restricted to ID or Antimicrobial Stewardship 

Imipenem/cilastatin/relebactam

Restricted to ID or Antimicrobial Stewardship 

Isavuconazole

Restricted to ID or Antimicrobial Stewardship except:​

1) Documented or suspected fungal pneumonia in a patient with prolonged QTc interval​

2) Prophylaxis against fungal infections in patients on the hematology/BMT service or lung transplant service with prolonged QTc interval or concurrent QTc prolonging medications.

Letermovir

Restricted to ID or Antimicrobial Stewardship except for:

1)  Adult malignant hematology service - for prophylaxis only per service guidelines
2)  Prophylaxis of CMV disease in high-risk kidney transplant recipients
3)  Continuation of current outpatient therapy

Maribavir

Restricted to ID or Antimicrobial Stewardship except:

1) Continuation of prior therapy

Meropenem/vaborbactam

Restricted to ID or Antimicrobial Stewardship except:

1) Continuation of prior therapy

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