Fecal microbiota spores, live—brpk (Vowst)

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dose  Notes
Secondary prevention from C. difficile infection

Take  4 capsules taken orally once daily for 3 consecutive days - 

Refer to prescribing information for administration considerations

No renal adjustment

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication

Dose

Notes 
Secondary prevention from C. difficile infection

Take  4 capsules taken orally once daily for 3 consecutive days - 

Refer to prescribing information for administration considerations

No renal adjustment

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

Restricted to ID/ASP for use in select adults with recurrent CDI who are expected to be hospitalized > 14 days after C. difficile episode.

ZSFG: Non-formulary

References: