UCSF Adult Restricted Antimicrobials

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Fecal microbiota spores, live—brpk (Vowst)

Restricted to ID/ASP for use in select adults with recurrent CDI who are expected to be hospitalized > 14 days after C. difficile episode.

Eravacycline

Restricted to ID or Antimicrobial Stewardship 

Daptomycin

Restricted to ID or Antimicrobial Stewardship

Dalbavancin

Restricted to ID or Antimicrobial Stewardship

Colistin IV

Restricted to ID or Antimicrobial Stewardship

*Inhaled use of colistin is allowed for unrestricted use in prophylaxis in lung transplant.

Cidofovir

Restrict to ID or Antimicrobial Stewardship except:

1) For treatment or prophylaxis against viral infection in a BMT patient

Ceftolozane/tazobactam (Zerbaxa)

Restricted to ID or Antimicrobial Stewardship

Ceftazidime/avibactam (Avycaz)

Restricted to ID or Antimicrobial Stewardship

Ceftaroline

Restricted to ID or Antimicrobial Stewardship

Cefiderocol

Restricted to ID or Antimicrobial Stewardship

Bezlotoxumab

Restricted to ID or Antimicrobial Stewardship

Additonal criteria for inpatient administration: Must be expected to be hospitalized > 14 days after C. difficile episode 

Baloxavir marboxil

Restricted to ID or Antimicrobial Stewardship

Artesunate

Restricted to ID or Antimicrobial Stewardship

Amikacin

Restricted to ID or Antimicrobial Stewardship for IV amikacin 

AmBisome (liposomal amphotericin B)

Restricted to ID or Antimicrobial Stewardship except:

1) Documented or suspected fungal pneumonia in a patient intolerant of or with contraindications to azoles

2) Prophylaxis against fungal infections in patients on the hematology/BMT service or lung transplant service

3) Empiric therapy for prolonged febrile neutropenia in hematology/oncology/BMT patient 

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