Dosing Weights

Different weights should be used for drugs dosed on a mg/kg basis depending on the physicochemical properties of the drug, as noted in the table below. For patients with extreme obesity or who are significantly underweight, or if toxicity is suspected, consult ID Pharmacy for dosing assistance.

Ideal and adjusted body weight calculator.

Drug Name	Adjustment in Obesity
Acyclovir IV	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
AmBisome (liposomal amphotericin B)	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Amikacin	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight Total Body Weight when <=120% of ideal body weight
Bezlotoxumab	Adjusted Body Weight when patient weight >120% of ideal body weight
Cidofovir	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Colistin IV	Ideal Body Weight when patient weight >120% of ideal body weight
Daptomycin	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Flucytosine	Ideal Body Weight when patient weight >120% of ideal body weight
Foscarnet (CMV dosing)	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Ganciclovir	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Gentamicin	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Miltefosine	Total Body Weight when <=120% of ideal body weight
Pentamidine IV	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Plazomicin	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Polymyxin B	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
TMP/SMX (trimethoprim/sulfamethoxazole)	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Tobramycin	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight
Voriconazole	Adjusted Body Weight when patient weight >120% of ideal body weight Total Body Weight when <=120% of ideal body weight

Infectious Diseases Management Program at UCSF

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