Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl >40 mL/min | 20-40 mL/min | 10-20 mL/min | <10 mL/min |
|---|---|---|---|---|
| All Indications | 25 mg/kg PO q6h | 25 mg/kg PO q12h | 25 mg/kg PO q24h | 25 mg/kg PO q48h |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
| All Indications | 25 mg/kg PO x1 now and post-HD | No data; consult ID pharmacy |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.