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| Revision | Operations | |
|---|---|---|
| 02-21-25 by kaipe | current revision | |
| 02-21-25 by kaipe | ||
| 02-21-25 by kaipe | ||
| 02-7-25 by ripal121 ripal121 replaced Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR with Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. via Scanner Search and Replace module. | ||
| 02-7-25 by ripal121 ripal121 replaced Intermittent HD with Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. via Scanner Search and Replace module. | ||
| 02-7-25 by conan.macdougal... [email protected] replaced For detailed view of dialysis dosing and evidence, see <a href="https://idmp.ucsfsitebuilder.acsitefactory.com/content/ucsf-adult-antimicrobial-dosing-dialysis-reference-document">Dosing in Hemodialysis</a> document.</p> with via Scanner Search and Replace module. | ||
| 07-31-24 by kaipe | ||
| 09-21-23 by ripal121 | ||
| 09-21-23 by ripal121 | ||
| 07-20-23 by ripal121 | ||
| 07-20-23 by ripal121 | ||
| 02-17-22 by [email protected] | ||
| 07-23-21 by conan.macdougal... | ||
| 08-19-20 by [email protected] | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 07-10-20 by [email protected] | ||
| 04-21-20 by ucsf_admin | ||
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | Dose | Notes |
|---|---|---|
| All Indications | 372 mg IV/PO Q8h x 6 doses (total of 48h), then 372 mg Q24h | No renal dose adjustment |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
| All Indications | 372 mg IV/PO Q8h x 6 doses (48h), then 372 mg IV/PO Q24h | No dose adjustment in hemodialysis |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR.
General Considerations
- For assistance with therapeutic drug monitoring (TDM), see Azole TDM Reference Document.
- Review medications for potential drug interactions.
- 372 mg of isavuconazonium = 200 mg of isavuconazole.
Restricted to ID or Antimicrobial Stewardship except:
1) Documented or suspected serious fungal infection in a patient with prolonged QTc interval
2) Prophylaxis against fungal infections in patients on the hematology/BMT service or lung transplant service with prolonged QTc interval or concurrent QTc prolonging medications.