Revisions for Pentamidine IV

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RevisionOperations
09-20-23 by Annie Kimcurrent revision
09-1-23 by ripal121
09-1-23 by ripal121
09-1-23 by ripal121
09-1-23 by ripal121
09-1-23 by ripal121
08-31-23 by ripal121
08-31-23 by ripal121

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication CrCl > = 10 ml/min CrCl < 10 ml/min
Pneumocystis pneumonia 4 mg/kg IV q24h 4 mg/kg IV q36h

*The current prescribing information does not provide specific renal adjustments and may need to consider other dosing outside of these recommendations. 

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication

Intermittent Hemodialysis

Continuous Hemodialysis
Pneumocystis pneumonia 4 mg/kg IV q24h (no adjustment for hemodialysis) 4 mg/kg IV q24h (no adjustment for hemodialysis)

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

*The current prescribing information does not provide specific renal adjustments and may need to consider other dosing outside of these recommendations.   

Restricted to ID or Antimicrobial Stewardship 

References: