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| Revision | Operations | |
|---|---|---|
| 07-20-23 by ripal121 | current revision | |
| 02-17-22 by [email protected] | ||
| 08-13-20 by conan.macdougal... | ||
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | eGFR >50mL/min/1.73m2 | 30-50 mL/min/1.73m2 | 15-30 mL/min/1.73m2 | <15 mL/min/1.73m2 |
|---|---|---|---|---|
|
All Indications 4 g = meropenem 2 g + vaborbactam 2 g |
4 g IV q8h over 3 hours | 2 g IV q8h over 3 hours | 2 g IV q12h over 3 hours | 1 g IV q12h over 3 hours |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
|
All Indications 4 g = meropenem 2 g + vaborbactam 2 g |
Adjust dose based on eGFR, dose post-HD | No data |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
Restricted to ID or Antimicrobial Stewardship except:
1) Continuation of prior therapy