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| Revision | Operations | |
|---|---|---|
| 02-7-25 by ripal121 ripal121 replaced Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR with Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. via Scanner Search and Replace module. | current revision | |
| 02-7-25 by ripal121 ripal121 replaced Intermittent HD with Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. via Scanner Search and Replace module. | ||
| 02-7-25 by conan.macdougal... [email protected] replaced For detailed view of dialysis dosing and evidence, see <a href="https://idmp.ucsfsitebuilder.acsitefactory.com/content/ucsf-adult-antimicrobial-dosing-dialysis-reference-document">Dosing in Hemodialysis</a> document.</p> with via Scanner Search and Replace module. | ||
| 10-26-23 by ripal121 | ||
| 10-26-23 by ripal121 | ||
| 10-26-23 by ripal121 | ||
| 10-26-23 by ripal121 | ||
| 07-20-23 by ripal121 | ||
| 02-17-22 by [email protected] | ||
| 08-13-20 by conan.macdougal... | ||
| 08-13-20 by conan.macdougal... | ||
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl > 30 mL/min | <30 mL/min |
|---|---|---|
| Single-dose regimen (skin/soft tissue infection) | 1500 mg IV x 1 dose | 1000 mg IV x 1 dose |
| Two-dose regimen (skin/soft tissue infection) | 1000 mg IV x 1 dose on day 1, then 500 mg IV X 1 on day 8 | 750 mg IV x 1 dose on day 1, then 375 mg IV X 1 on day 8 |
| Complicated Gram-positive infections (e.g. Native osteomyelitis)* | 1500 mg IV on days 1 & 8 | 1000 mg IV on days 1 & 8 |
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*ID consult highly recommended for patient-specific recommendations. *For dosing in other complicated indications, contact ID or ID pharmacy. |
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Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
| Complicated Gram-positive infections (e.g. Native osteomyelitis)* | 1500 mg IV on days 1 & 8 | No dose adjustment necessary for hemodialysis |
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*ID consult highly recommended for patient-specific recommendations. *For dosing in other complicated indications, contact ID or ID pharmacy. |
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Dialysis Notes
Other dosing strategies used for treatment of bone/joint infections or bacteremia.
Restricted to ID or Antimicrobial Stewardship