Patient Population: Adult
| Diagnosis | Common Pathogens | Drug(s) of First Choice | Alternative Drug(s) | Comments | Expected Duration |
|---|---|---|---|---|---|
| Community Acquired Sepsis with Unknown Source |
Enterobacteriaceae S. aureus Streptococci spp. |
PLUS one of: OR OR Ertapenem (if known prior ESBL isolation) |
For severe beta-lactam allergy: PLUS PLUS |
Follow empiric therapy based upon source or clinical syndrome, if known (e.g. pneumonia, UTI, etc.) |
Stop antibiotics at 48 hours if work-up does not reveal a source of infection Duration should otherwise be tailored to clinical or microbiological source |