Primary tabs
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | Dose | Notes |
|---|---|---|
| Standard Dose | 1 g IV q24h | No renal dose adjustment |
| Serious Infections, Non-enterococcal Endocarditis, Osteomyelitis, Septic Arthritis | 2 g IV q24h | No renal dose adjustment |
|
Meningitis & Enteroccocal Endocarditis (in combination with ampicillin) |
2 g IV q12h | No renal dose adjustment |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
| Usual dose | 1 g IV q24h |
No dose adjustment for hemodialysis |
| Endocarditis & Osteomyelitis | 2 g IV q24h | |
|
Meningitis & Enteroccocal Endocarditis (in combination with ampicillin) |
2 g IV q12h |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.