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02-7-25 by ripal121 ripal121 replaced Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR with Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. via Scanner Search and Replace module. | current revision | |
02-7-25 by ripal121 ripal121 replaced Intermittent HD with Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. via Scanner Search and Replace module. | ||
02-7-25 by conan.macdougal... [email protected] replaced For detailed view of dialysis dosing and evidence, see <a href="https://idmp.ucsfsitebuilder.acsitefactory.com/content/ucsf-adult-antimicrobial-dosing-dialysis-reference-document">Dosing in Hemodialysis</a> document.</p> with via Scanner Search and Replace module. | ||
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04-20-20 by ucsf_admin | ||
04-20-20 by ucsf_admin |
Dosing: Adult Antimicrobial Dosing, Non-dialysis
This dosing aligns with current practices at the SFDPH TB Clinic (as of 5/2023) for treatment of tuberculosis. For patients in other counties, contact the respective TB clinics for dosing recommendations.
Weight | CrCl > 30 mL/min | < 30 mL/min |
---|---|---|
30-40 kg | 600 mg PO q24h | 20-25 mg/kg PO three times weekly |
41-50 kg | 800 mg PO q24h | 20-25 mg/kg PO three times weekly |
51-60 kg | 1000 mg PO q24h | 20-25 mg/kg PO three times weekly |
61-70 kg | 1200 mg PO q24h | 20-25 mg/kg PO three times weekly |
71-80 kg | 1400 mg PO q24h | 20-25 mg/kg PO three times weekly |
81-90 kg | 1600 mg PO q24h | 20-25 mg/kg PO three times weekly |
> 91 kg | Consult ID or ID pharmacy | Consult ID or ID pharmacy |
Therapeutic drug monitoring may be utilized under the guidance of SF TB Clinic, ID, and/or ID/ASP Pharmacy. Higher dosing may be required.
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
---|---|---|
All Indications | 20-25 mg/kg PO x1 now and post-HD | 15-20 mg/kg PO q24h |
Therapeutic drug monitoring may be utilized under the guidance of SF TB Clinic, ID, and/or ID/ASP Pharmacy. Higher dosing may be required.
Dialysis Notes
Drug is available in 400mg and 100mg tablets.
This dosing aligns with current practices at the SFDPH TB Clinic (as of 5/2023) for treatment of tuberculosis. For patients in other counties, contact the respective TB clinics for dosing recommendations.