Ethambutol

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Weight CrCl > 30 mL/min < 30 mL/min
41-53 kg 800 mg PO q24h 15-25 mg/kg PO three times weekly
54-67 kg 1000 mg PO q24h 15-25 mg/kg PO three times weekly
68-80 kg 1200 mg PO q24h 15-25 mg/kg PO three times weekly
81-94 kg 1400 mg PO q24h 15-25 mg/kg PO three times weekly
95-107 kg 1600 mg PO q24h 15-25 mg/kg PO three times weekly
>108 kg Consult ID or ID pharmacy Consult ID or ID pharmacy

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication

Intermittent Hemodialysis

Continuous Hemodialysis
All Indications 15 -25 mg/kg PO x1 now and post-HD 15-20 mg/kg PO q24h

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

Dose based on ideal body weight. Drug is available in 400mg and 100mg tablets.