Dosing Weights
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl > 30 mL/min | < 30 mL/min |
|---|---|---|
| All indications | 8 – 10* mg/kg IV q24h | 8 – 10* mg/kg IV q48h |
*Doses up to 12 mg/kg may be indicated in treatment of some VRE infections - confer with ID/ID pharmacy.
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis* |
|---|---|---|
| All Indications |
8-10 mg/kg IV x1 now and post-HD Alternate for patients not on stable dialysis schedule: 8-10 mg/kg IV q48h |
6-8 mg/kg IV q 24h Flow rates exceeding 2.5 L/hour may require higher dosing Contact ID/ASP pharmacy for assistance |
*These recommendations have not been evaluated for patients receiving continuous renal replacement therapy other than CVVHD (ex. CVVH).
Dialysis Notes
Not effective in treatment of pneumonia.
Restricted to ID or Antimicrobial Stewardship