Revisions for Cefoxitin

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01-11-24 by kaipecurrent revision
01-11-24 by kaipe

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication CrCl >50 mL/min CrCl 30-50 mL/min CrCl 10-29 mL/min CrCl <10 mL/min
Standard dosing, NTM infection 2 g IV q6h 2 g IV q8h 2 g IV q12h 1 g IV q24h

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication

Intermittent Hemodialysis

Continuous Hemodialysis
Standard dosing, NTM infection 1 g q24h (on days of HD, give after HD) 2 g IV q8h*

*Limited data exist for CRRT dosing. Consider alternative antibiotic. May dose for CrCl 30 to 50 mL/minute if necessary.

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

References: