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| Revision | Operations | |
|---|---|---|
| 08-30-24 by [email protected] | current revision | |
| 08-15-24 by [email protected] | ||
| 08-15-24 by [email protected] | ||
| 01-18-23 by kaipe | ||
| 01-18-23 by kaipe | ||
| 01-11-23 by kaipe | ||
| 01-11-23 by kaipe | ||
| 02-17-22 by [email protected] | ||
| 10-20-20 by conan.macdougal... | ||
| 08-26-20 by conan.macdougal... | ||
| 08-21-20 by [email protected] | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 08-12-20 by conan.macdougal... | ||
| 07-10-20 by [email protected] | ||
| 06-23-20 by conan.macdougal... | ||
| 04-21-20 by ucsf_admin | ||
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl > 20 mL/min | <20 mL/min |
|---|---|---|
|
UCSF: All Infections, including documented/suspected Pseudomonas UCSF exclusion criteria for EXTENDED INFUSION: resistant or intermediate susceptibility organism, cystic fibrosis, peri-procedural areas, insufficient IV access ZSFG: Use EXTENDED INFUSION when recommended by ID pharmacist or ID fellow |
Loading dose = 4.5 g IV over 30 min x1, then 4.5 g IV infused over 4h every 8h (starting 4h after loading dose) | Use SHORT INFUSION piperacillin/tazobactam |
See Adult Extended Infusion Piperacillin/Tazobactam Protocol for additional details.
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
|
UCSF: All Infections, including documented/suspected Pseudomonas UCSF: Exclusion criteria for EXTENDED INFUSION: resistant or intermediate susceptibility organism, cystic fibrosis, peri-procedural areas, insufficient IV access |
Use SHORT INFUSION piperacillin/tazobactam |
UCSF: Loading dose = 4.5 g IV over 30 min x1, then 4.5 g IV infused over 4h every 8h (starting 4h after loading dose) ZSFG: 4.5 g IV q8h (SHORT infusion over 30 minutes) |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
UCSF: PREFERRED dosing strategy if no exclusions
ZSFG: Available upon ID pharmacy or ID fellow recommendation