Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | Dose | Notes |
|---|---|---|
| Standard Dose* | 1 g IV q24h | No renal dose adjustment |
| Serious Infections, Non-enterococcal Endocarditis, Osteomyelitis, Septic Arthritis, Epidural Abscess, Intra-abdominal Infections, Liver Abscesses, Septic Shock** | 2 g IV q24h | No renal dose adjustment |
|
Meningitis & Enteroccocal Endocarditis (in combination with ampicillin)** |
2 g IV q12h |
No renal dose adjustment |
*In patients with obesity (defined as BMI >30 kg/m2), recommend using a minimum of 2 g daily.
** In patients with obesity (defined as BMI >30 kg/m2), higher dosing may be indicated based on patient-specific factors, contact ID/ASP pharmacy for assistance.
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
| Standard dose* | 1 g IV q24h |
No dose adjustment for hemodialysis |
| Serious Infections, Non-enterococcal Endocarditis, Osteomyelitis, Septic Arthritis, Epidural Abscess, Intra-abdominal Infections, Liver Abscesses, Septic Shock** | 2 g IV q24h | |
|
Meningitis & Enteroccocal Endocarditis (in combination with ampicillin)** |
2 g IV q12h |
*In patients with obesity (defined as BMI >30 kg/m2), recommend using a minimum of 2 g daily.
** In patients with obesity (defined as BMI >30 kg/m2), higher dosing may be indicated based on patient-specific factors, contact ID/ASP pharmacy for assistance.