Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl ≥50 mL/min | 30-49 mL/min | 10-29 mL/min | <10 mL/min |
|---|---|---|---|---|
|
Respiratory Syncytial Virus (RSV) Use total body weight for dosing |
40-49 kg = 400 mg PO q12h 50-59 kg = 400 mg PO qAM PLUS 600 mg PO qPM 60-69 kg = 600 mg PO q12h 70-79 kg = 600 mg PO qAM PLUS 800 mg PO qPM 80-89 kg = 800 mg PO q12h 90 kg or greater = 600 mg PO q8h |
40-59 kg = 200 mg PO q12h 60 kg or greater = 200 mg PO q8h |
200 mg PO daily | 200 mg PO daily (consider contacting ID/ASP pharmacist) |
| Hepatitis C | Dosing is highly individualized. Refer to www.hcvguidelines.org for detailed information on appropriate indications for ribavirin in the treatment of hepatitis C infection. | |||
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
|
Respiratory Syncytial Virus (RSV) Use total body weight for dosing |
200 mg PO daily (give daily - on days of hemodialysis, give dose afterwards) |
40-59 kg = 200 mg PO q12h 60 kg or greater = 200 mg PO q8h |
| Hepatitis C |
Dosing is highly individualized. Refer to www.hcvguidelines.org for detailed information on appropriate indications for ribavirin in the treatment of hepatitis C infection. |
|
Dialysis Notes
For treatment of respiratory syncytial virus (RSV) in adult patients at UCSF, refer to the RSV Treatment Guideline.