Minocycline

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dosing Notes
All Indications 200 mg IV/PO x1, then 100 mg IV/PO q12h No adjustment for renal dysfunction

*There may be certain situations that may require higher dosing (200 mg IV/PO q12h).  Speak to ASP/ID pharmacy if needed.

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication Dosing Notes
All Indications 200 mg IV/PO x1, then 100 mg IV/PO q12h No adjustment for hemodialysis

*There may be certain situations that may require higher dosing (200 mg IV/PO q12h).  Speak to ASP/ID pharmacy if needed.

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

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