Ampicillin

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication

CrCl > 50 mL/min

10 - 50 mL/min

< 10 mL/min

Uncomplicated infection 2 g IV q6h 1 g IV q6h 1 g IV q12h
Meningitis or endovascular infection 2 g IV q4h 2 g IV q6h 1 g IV q8h 

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication

Intermittent Hemodialysis

Continuous Hemodialysis
Uncomplicated Infection 2 g IV x1 now, then qPM 2 g IV q8h
Meningitis or endovascular infection 2 g IV q12h 2 g IV q6h

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.