These dosing recommendations are meant as guidance based on available literature and should not replace clinical judgement. Antimicrobial dosing should take into account factors specific to the patient (weight, renal function), antimicrobial (pharmacokinetics, pharmacodynamics, toxicity) and disease-state.
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1 Drugs
Ciprofloxacin
| Indication | CrCl > 50 mL/min | 30 - 50 mL/min | < 30 mL/min |
|---|---|---|---|
|
400 mg IV q12h 500 mg PO BID |
400 mg IV q12h 500 mg PO BID |
400 mg IV q24h 500 mg PO daily |
|
| Pseudomonas infections, bloodstream infections, & induction therapy for Staphylococcus hardware infections +/- rifampin |
400 mg IV q8h 750 mg PO q12h |
400 mg IV q12h 500 mg PO q12h |
400 mg IV q24h 500 mg PO daily |
