Ciprofloxacin

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication CrCl > 50 mL/min 30 - 50 mL/min < 30 mL/min
 

400 mg IV q12h

500 mg PO BID

400 mg IV q12h

500 mg PO BID

400 mg IV q24h

500 mg PO daily

Pseudomonas infections & bloodstream infections

400 mg IV q8h

750 mg PO q12h

400 mg IV q12h

500 mg PO q12h

400 mg IV q24h

500 mg PO daily

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication

Intermittent Hemodialysis

Continuous Hemodialysis
All Indications 400 mg IV qPM or 500 mg PO qPM 400 mg IV q12h or 500 mg PO q12h

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

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