N/A-testing NOT APPLICABLE to organism. CZOL-cefazolin, CTRX-ceftriaxone, CTAZ-ceftazidime, CFPM-cefepime, GEN-gentamicin, TOB-tobramycin, T/S-trimethoprim/sulfamethoxazole, CIP-ciprofloxacin, IMI-imipenem-cilastatin, MER-meropenem, P/T-piperacillin-tazobactam
Values are % of strains testing susceptible to listed antibiotic. Unless indicated, results are for all inpatient/ED locations and culture sites.
Susceptibilities are based on data from 2020-2022. Isolate numbers and 95% confidence intervals are provided to gauge precision of susceptibility estimate.
Organism | Total Isolates* |
CTRX %S (95% CI) |
CTAZ %S (95% CI) |
CFPM %S (95% CI) |
GEN %S (95% CI) |
TOB %S (95% CI) |
T/S %S (95% CI) |
CIP %S (95% CI) |
P/T %S (95% CI) |
MER/IMI** %S (95% CI) |
Enterobacter cloacae |
61 |
N/A |
N/A |
89 (98)# (78,94) |
100 (94,100) |
98 (91,100) |
98 (91,100) |
95 (87,98) |
72 (60,82) |
98 (91,100) |
Escherichia coli |
290 |
87 (83,91) |
94 (91,96) |
93 (96)# (90,95) |
91 (88,94) |
92 (88,95) |
65 (60,71) |
77 (73,82) |
96 (93,98) |
100 (99,100) |
Klebsiella oxytoca |
68 |
86 (77,93) |
97 (90,99) |
96 (95)# (88,98) |
97 (90,99) |
95 (89,98) |
89 (80,95) |
94 (86,98) |
83 (73,90) |
100 (95,100) |
Klebsiella pneumoniae |
88 |
88 (80,94) |
88 (80,94) |
92 (95)# (84,96) |
88 (86,97) |
95 (89,98) |
77 (67,85) |
81 (72,88) |
98 (94,100) |
100 (96,100) |
Pseudomonas aeruginosa | 109* | N/A |
88 (81,93) |
92 (86,96) |
N/A |
94 (89,97) |
N/A |
86 (79,91) |
83 (75,91) |
91 (84,95) |
Serratia marcescens |
43 |
95 (85,99) |
100 (92,100) |
97 (100)# |
95 (85,99) |
93 (81,98) |
97 (88,100) |
95 |
97 (88,100) |
100 (92,100) |
*Pseudomonas aeruginosa isolates do not include isolates from patients with cystic fibrosis.
**Due to a change in susceptibility testing method, urine isolates from 2022 onward are tested for ertapenem and imipenem-cilastatin but not meropenem. Reported combined susceptibility to meropenem or imipenem-cilastatin is based on meropenem for non-urine isolates and imipenem-cilastatin for urine isolates. This should be considered an approximate estimate of population susceptibility because susceptibility of each of these antibiotics cannot be completely inferred from the other.
# Number in parentheses represents the percentage of isolates both fully susceptible and susceptible-dose dependent to cefepime, for each organism. Susceptible-dose dependent isolates of Enterobacteriaceae are those with MIC 4 to 8 micrograms/mL for a cefepime dose of 50 mg/kg/dose iv q8h with maximum 2g/dose, as routinely recommended per BCH Pediatric Antimicrobial Dosing Guidelines, is anticipated to be active.