The predominant organism causing urinary tract infections among outpatients is E. coli. Sensitivities for E. coli isolates submitted for outpatients in 2019-2021 are summarized below. Isolate numbers and 95% confidence intervals are provided to gauge precision of susceptibility estimate.
| Drug | Percent susceptible (of 106 isolates; 95% CI) |
| Cephalexin* | 97 (91, 99) |
| TMP/SMX | 79 (71,86) |
| Ciprofloxacin | 86 (79,92) |
| Nitrofurantoin** | 100 (97,100) |
* Cephalexin susceptibility determined using breakpoint = 16 for uncomplicated UTI, based on cefazolin MIC
** Nitrofurantoin should only be used for cystitis, in patients with CrCl>60ml/min