UCSF Benioff Children's Hospital Antimicrobial Susceptibility: E. coli Susceptibility Among Outpatients

The predominant organism causing urinary tract infections among outpatients is E. coli.  Sensitivities for E. coli isolates submitted for outpatients in 2019-2021 are summarized below. Isolate numbers and 95% confidence intervals are provided to gauge precision of susceptibility estimate. 

Drug Percent susceptible (of 106 isolates; 95% CI)
Cephalexin* 97 (91, 99)
TMP/SMX 79 (71,86)
Ciprofloxacin 86 (79,92)
Nitrofurantoin** 100 (97,100)

* Cephalexin susceptibility determined using breakpoint = 16 for uncomplicated UTI, based on cefazolin MIC

** Nitrofurantoin should only be used for cystitis, in patients with CrCl>60ml/min