The predominant organism causing urinary tract infections among outpatients is E. coli. Sensitivities for E. coli isolates submitted for outpatients in 2020-2022 are summarized below. Isolate numbers and 95% confidence intervals are provided to gauge precision of susceptibility estimate.
Drug | Percent susceptible (of 112 isolates; 95% CI) |
Cephalexin* | Pending update** |
TMP/SMX | 83 (75,89) |
Ciprofloxacin | 87 (80,92) |
Nitrofurantoin** | 100 (97,100) |
* Cephalexin susceptibility determined using breakpoint = 16 for uncomplicated UTI, based on cefazolin MIC
** Previous susceptibility 2019-2021 based on 106 isolates = 97% (91, 99). Cephalexin susceptibility report is not yet updated for 2022 due to need for further report validation.
*** Nitrofurantoin should only be used for cystitis, in patients with CrCl>60ml/min