Brain abscess

Diagnosis Common Pathogens Drug(s) of First Choice Alternative Drug(s) Comments Expected Duration
Brain abscess

Streptococci (anaerobic or aerobic)

Bacteroides spp

Prevotella spp

Enterobacteriaceae

Ceftriaxone 2g IV q12h

PLUS

Metronidazole

WITH OR WITHOUT*

Vancomycin

 

For severe PCN allergy:

Aztreonam 2g IV q8h

PLUS

Vancomycin

PLUS

Metronidazole

*Add vancomycin if patient at risk for drug-resistant streptococci or MRSA

ID consultation recommended