Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | Dose |
|---|---|
| Primary, secondary, early latent syphilis | 2.4 million units IM x 1 |
| Late latent syphilis | 2.4 million units IM once weekly x 3 doses |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
| Primary, secondary, early latent syphilis | 2.4 million units IM x 1 | No dose adjustment for hemodialysis |
| Late latent syphilis | 2.4 million units IM once weekly x 3 doses |
Dialysis Notes
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.
Restricted during Bicillin L-A shortage (2025 - est resolution Q4 2027)