Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | Dose | Notes |
|---|---|---|
| Clostridioides difficile infection: initial episode, non-fulminant | 125 mg PO QID | No renal dose adjustment |
| Clostridioides difficile infection: fulminant | 500 mg PO QID* |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
| Clostridioides difficile infection: non-fulminant | 125 mg PO QID | No dose adjustment in hemodialysis |
| Clostridioides difficile infection: fulminant | 500 mg PO QID |
Dialysis Notes
*Consider additional rectal instillation
See IDMP guidelines for greater detail and vancomycin taper dosing: Adult C. difficile Infection Guideline
PO vancomycin is NOT sufficiently absorbed to treat systemic infections