Rifampin

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dosing Notes
Mycobacterial infections 600 mg IV/PO q24h

 

No renal dose adjustment

Prosthetic device infections 300 mg IV/PO q12h
Endocarditis 300 mg IV/PO q8h

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication Dosing Notes
Mycobacterial infections 600 mg IV/PO q24h

 

No adjustment in hemodialysis

Prosthetic device infections 300 mg IV/PO q12h
Endocarditis 300 mg IV/PO q8h

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

Review medications for potential drug interactions.

References: