Dosing: Adult Antimicrobial Dosing, Non-dialysis

CrCl>30 ml/min CrCl<30 ml/min
200 mg IV x1 then 100 mg IV q24h No dosage required; consider risk/benefit

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis


Intermittent Hemodialysis

Continuous Hemodialysis
  No adjustment for dialysis No adjustment for dialysis

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

All use requires approval by COVID attending