Primary tabs
Dosing Weights
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl > 30 mL/min | < 30 mL/min |
|---|---|---|
| All Indications |
20-25 mg/kg PO q24h: 40-55 kg: 1000mg q24h 56-75 kg: 1500mg q24h 76-90 kg: 2000mg q24h >=90 kg: Contact ID/ID pharmacy |
20-25 mg/kg PO three times weekly |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
| All Indications | 20-25 mg/kg PO x1 now and post-HD | 20-25 mg/kg PO q24h |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.
Dosing in obesity (BMI > 30): use lean body weight (see online calculator).
Supplied as 500mg tablets
This dosing aligns with current practices at the SFDPH TB Clinic (as of 8/2022). For patients in other counties, contact the respective TB clinics for dosing recommendations.