Primary tabs
Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | CrCl > 30 mL/min | < 30 mL/min |
|---|---|---|
| All Indications |
20-25 mg/kg PO q24h: 36-39 kg: 750 mg PO q24h 40-50 kg: 1000mg PO q24h 51-59 kg: 1250 mg PO q24h 60-70 kg: 1500mg PO q24h 71-80 kg: 1750 mg PO q24h > 81 kg: 2000 mg PO q24h |
25-30 mg/kg PO three times weekly |
Supplied as 500 mg tablets
This dosing aligns with current practices at the SFDPH TB Clinic (as of 5/2023). For patients in other counties, contact the respective TB clinics for dosing recommendations.
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
| All Indications | 20-25 mg/kg PO x1 now and post-HD | 20-25 mg/kg PO q24h |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.