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Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | Dose | Notes |
|---|---|---|
|
Meningococcal prophylaxis in patients in addition to meningococcal vaccination; Patients on a C5 inhibitor |
500 mg po q12h | No renal adjustment needed |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
| Indication | Dose | Notes |
|---|---|---|
|
Meningococcal prophylaxis in patients in addition to meningococcal vaccination; Patients on a C5 inhibitor |
500 mg po q12h | No renal adjustment needed |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.