Nafcillin

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dosing Notes
Meningitis, osteomyelitis, bloodstream infection, or endovascular infection 2 g IV Q4h

No renal dose adjustment

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication Dosing Notes
Meningitis, osteomyelitis, bloodstream infection, or endovascular infection 2 g IV Q4h

No dose adjustment in hemodialysis

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

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