Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dosing Notes
All Indications 300 mg PO Q24h No renal dose adjustment

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis


Intermittent Hemodialysis

Continuous Hemodialysis
All Indications 300mg PO qPM 300mg PO q24h

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

Any patients with confirmed or suspected active TB disease are required by law to be reported within 1 working day of identification to the TB Control Section.  For more detail see:,554-3613%20for%20urgent%20reporting