Fidaxomicin

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dosing Notes
Clostridium difficile infection 200 mg PO q12h No adjustment for renal dysfunction

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication Dosing Notes
Clostridium difficile infection 200 mg PO q12h No adjustment for hemodialysis

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

All use requires authorization from the Antimicrobial Stewardship Program or the consulting ID fellow

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