Clindamycin

Dosing: Adult Antimicrobial Dosing, Non-dialysis

Indication Dose Notes
 

600 mg IV q8h

450 mg PO q8h

No renal dose adjustment
Necrotizing Soft Tissue Infection & Group A Streptococcus Infection 900 mg IV Q8h No renal dose adjustment

Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis

Indication Dose Notes
Uncomplicated Infection

600 mg IV q8h

450 mg PO q8h

 

No dose adjustment in hemodialysis

Necrotizing Soft Tissue Infection & Group A Streptococcus Infection 900 mg IV Q8h

Dialysis Notes

Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min.  For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.

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