Dosing: Adult Antimicrobial Dosing, Non-dialysis
| Indication | >30 mL/min | 15-29 mL/min | <15 mL/min |
|---|---|---|---|
| Most Indications | 500 mg PO QID or 1000 mg PO TID | 250-500 mg PO TID | 250-500 mg PO BID |
| Uncomplicated Cystitis or Streptococcal Pharyngitis | 500 mg PO BID | 250 mg PO BID | 250 mg PO daily |
Dosing: Antimicrobial Dosing in Intermittent & Continuous Hemodialysis
|
Indication |
Intermittent Hemodialysis |
Continuous Hemodialysis |
|---|---|---|
| Most Indications | 250 mg PO BID | No data |
| Uncomplicated Cystitis or Streptococcal Pharyngitis | 250 mg PO daily | No data |
Dialysis Notes
Intermittent HD assumes high-flux hemodialysis. CRRT assumes CVVHD with ultrafiltration rate 2L/h and residual native GFR < 10 mL/min. For detailed view of dialysis dosing and evidence, see Dosing in Hemodialysis document.