Cellulitis

Group A streptococcus 

Staphylococcus aureus  

Outpatient: 

Cephalexin
25 mg/kg/dose (max 500 mg/dose) enterally tid  

--------------------- 

Inpatient/need for IV therapy: 

Cefazolin
25 mg/kg/dose (max 2000 mg/dose) IV q8h  

Penicillin or cephalosporin allergy with higher risk for allergic reaction: 

Clindamycin
10 mg/kg/dose (max 900 mg/dose) IV q8h  

OR  

Clindamycin
10 mg/kg/dose (max 600 mg/dose) enterally tid 

Duration: 5 days for non-severe infection 

ID consult recommended for severe infection, indicated by hemodynamic instability, end-organ dysfunction, or extensive local progression