UCSF Benioff Children's Hospital Antimicrobial Susceptibility: Vancomycin Minimum Inhibitory Concentrations Among Staphylococcus aureus

Some studies have associated higher minimum inhibitory concentrations (MICs) in Staphylococcus aureus with an increased likelihood of therapeutic failure. (Note: to date, studies do not indicate a strong relationship between vancomycin MIC and outcomes in Staphylococcus epidermidis, where a vancomycin MIC of 2 is common).

Pediatric Inpatient Vancomycin MIC Distribution for S. aureus

Vancomycin MIC (all S. aureus) 2019-2021 (n=334 total)
0.5 5 (1.5%)
1 321 (96.1%)
2 8 (2.4%)