Pediatric Guidelines: Sexually Transmitted Infections (Adolescent) - Gonorrhea

Condition Major Pathogens First Choice Therapy Alternative Therapy Comments
Gonorrhea (uncomplicated) Neisseria gonorrhoeae

Ceftriaxone 250mg IM x 1


Azithromycin 1g PO x 1


Sexual partners should be treated

Obtain culture with treatment failure or alternative regimens

This guideline is for uncomplicated gonorrhea. If clinical findings suggest pelvic inflammatory disease, click here for PID guidelines. 

Reference: Workowski KA, Bolan GA, Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. Morbid Mortal Wkly Recomm Rep 2015;64:1-138.

These are guidelines only and not intended to replace clinical judgment. Modification of therapy may be indicated based on patient comorbidities, previous antibiotic therapy or infection history. Doses provided are usual doses but may require modification based on patient age or comorbid conditions. Refer to Pediatric Antimicrobial Dosing Guideline for further guidance on dosing in children, and Neonatal Dosing Guideline for infants < 1 month of age. Consult a pediatric pharmacist for individualized renal or hepatic dose adjustment. For additional guidance, please contact Pediatric Infectious Diseases (ID) or the Pediatric Antimicrobial Stewardship Program (ASP).