Traveler’s diarrhea

Diagnosis Common Pathogens Drug(s) of First Choice Alternative Drug(s) Comments Expected Duration

Empiric treatment while abroad

Toxigenic E. coli

Salmonella

Shigella

Campylobacter

Mild, self-limited cases can be treated with fluid and electrolyte repletion +/- bismuth subsalicylate.

Azithromycin 500mg PO daily x 3 days OR

Ciprofloxacin 500 mg PO BID x 1 - 3 days OR

Rifaximin
 

EITHER WITH or WITHOUT

Loperamide 4 mg PO x1; then 2 mg after each loose stool,

MAX 16 mg/day

0-3 days

Clinical Infectious Diseases, Volume 65, Issue 12, 29 November 2017, Pages e45–e80, https://doi.org/10.1093/cid/cix669