Patient Population: Adult
| Diagnosis | Common Pathogens | Drug(s) of First Choice | Alternative Drug(s) | Comments | Expected Duration |
|---|---|---|---|---|---|
| (major peritoneal soilage, large or multiple abscesses, patient hemodynamically unstable) |
E. coli Klebsiella B. fragilis P. aeruginosa Enterococcus spp. Streptococcus spp S. aureus |
PLUS OR Meropenem* |
For severe PCN allergy: PLUS PLUS Metronidazole |
*For hemodynamically unstable health-care associated infection, consider meropenem Fungal coverage rarely needed empirically but consider in high-risk patients: critically ill with upper GI source, recurrent bowel perforation, heavy colonization, surgically-treated pancreatitis |
ID consultation is recommended |