Enterobacteriaceae (e.g. E. coli, Proteus)

P. aeruginosa (less common)

Ertapenem
OR
Piperacillin/
Tazobactam

For severe PCN allergy:
Aztreonam
WITH OR WITHOUT:
Vancomycin

Criteria: signs and symptoms compatible with a UTI, no other identified source of infection, & ≥ 100,000 cfu of  ≥ 1 bacterial species on urine culture

Pyuria alone is not an indication for treatment.

A negative urinalysis suggests an alternative source of infection.

Remove catheter if possible.

Switch to oral therapy when susceptibilities known and patient stable