Patient Population: Adult
Diagnosis | Common Pathogens | Drug(s) of First Choice | Alternative Drug(s) | Comments | Expected Duration |
---|---|---|---|---|---|
Healthcare-associated secondary peritonitis Mild-Moderate intra-abdominal abscess (including post-op pelvic abscesses) |
E. coli Klebsiella B. fragilis Streptococci spp S. aureus Enterococcus |
OR |
Vancomycin PLUS Aztreonam PLUS Metronidazole |
Fungal coverage rarely needed empirically but consider in high-risk patients: critically ill with upper GI source, recurrent bowel perforation, heavy colonization, surgically-treated pancreatitis |
Stop antibiotics 4 days after source control achieved If source control is not obtained, consultation with ID recommended |
Clinical Infectious Diseases, Volume 50, Issue 2, 15 January 2010, Pages 133–164, https://doi.org/10.1086/649554