Patient Population: Adult
| Diagnosis | Common Pathogens | Drug(s) of First Choice | Alternative Drug(s) | Comments | Expected Duration |
|---|---|---|---|---|---|
|
Diverticulitis For severe infection, refer to severe secondary peritonitis |
E. coli Klebsiella B. fragilis Streptococci spp |
Inpatient: Ceftriaxone PLUS Metronidazole Outpatient: Amoxicillin/clavulanic acid 875/125 mg po TID OR |
For severe beta-lactam allergy: Inpatient: Vancomycin PLUS PLUS Outpatient: PLUS Metronidazole |
Management without antibiotics can be considered in patients with uncomplicated disease (no signs of severe infection, no evidence of fistula or abscess, not immunosuppressed) | 10 days (can step down to oral therapy to complete course) |