Community-acquired secondary peritonitis: Mild-Moderate intra-abdominal abscess

Diagnosis Common Pathogens Drug(s) of First Choice Alternative Drug(s) Comments Expected Duration

Community-acquired secondary peritonitis

Mild-Moderate intra-abdominal abscess

E. coli

Klebsiella

B. fragilis

Streptococci spp

Ceftriaxone 

PLUS Metronidazole

OR Ertapenem

For severe beta-lactam allergy:

Vancomycin

PLUS

Aztreonam

PLUS

Metronidazole

 

Stop antibiotics 4 days after source control achieved

If source control is not obtained, consultation with ID recommended

Clinical Infectious Diseases, Volume 50, Issue 2, 15 January 2010, Pages 133–164, https://doi.org/10.1086/649554